Radiofrequency Thermal Ablation offers a safe and effective option for patients with inoperable or recurrent liver cancer who have failed to respond to conventional methods. Many times RFA can be an alternative to surgery. Recent developments in radiofrequency thermal ablation (RFA) have expanded the treatment options for certain patients. Minimally invasive, image-guided therapy provides effective localized treatment of isolated neoplastic disease, and can also be used as an adjunct to conventional surgery, systemic chemotherapy, or radiation. RFA expands the medical application of heat, which is a cautery device to cut tissue. In the procedure, the tumors are located with ultrasound, computed tomography (CT), or magnetic resonance (MR) imaging devices. Then, essentially the patient is turned into an electrical circuit by placing grounding pads on the thighs. A small needle-electrode with an insulated shaft and an uninsulated distal tip is inserted through the skin and directly into the tumor. Ionic vibration at the needle tip leads to frictional heat. After 10 to 30 minutes of contact with the tumor, the radiofrequency energy kills a 2.5- to 5-cm sphere.  The dead cells are not removed, but become scar tissue and eventually shrink. Radiofrequency thermal ablation can usually be performed as an outpatient procedure under general anesthesia or conscious sedation.